GBA2 antibody
Product Specifications
Background
Non-lysosomal glucosylceramidase that catalyzes the conversion of glucosylceramide (GlcCer) to free glucose and ceramide. Involved in sphingomyelin generation and prevention of glycolipid accumulation. May also catalyze the hydrolysis of bile acid 3-O-glucosides, however, the relevance of such activity is unclear in vivo. Plays a role in central nevous system development. Required for proper formation of motor neuron axons.
Synonyms
Non-lysosomal glucosylceramidase (NLGase) |Beta-glucocerebrosidase 2 (Beta-glucosidase 2) |Bile acid beta-glucosidase GBA2|Bile acid glucosyl transferase GBA2|Cholesterol glucosyltransferase GBA2|Cholesteryl-beta-glucosidase GBA2|Glucosylceramidase 2|Non-lysosomal cholesterol glycosyltransferase|Non-lysosomal galactosylceramidase|Non-lysosomal glycosylceramidase|GBA2|KIAA1605|SPG46
Gene ID
57704
UniProt
Q9HCG7
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Glucosidase, beta (bile acid) 2
Target
GBA2
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA
Field of Research
Metabolism
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA
Curated Selection
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