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GAR1 antibody

Product Specifications

Background

Required for ribosome biogenesis and telomere maintenance. Part of the H/ACA small nucleolar ribonucleoprotein(H/ACA snoRNP) complex, which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Each rRNA can contain up to 100 pseudouridine("psi") residues, which may serve to stabilize the conformation of rRNAs. May also be required for correct processing or intranuclear trafficking of TERC, the RNA component of the telomerase reverse transcriptase(TERT) holoenzyme.

CAS Number

9007-83-4

Synonyms

H/ACA ribonucleoprotein complex subunit 1|Nucleolar protein family A member 1|snoRNP protein GAR1|GAR1|NOLA1

Gene ID

54433

UniProt

Q9NY12

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

GAR1 ribonucleoprotein homolog(yeast)

Target

GAR1

Clonality

Polyclonal

Isotype

IgG

Applications

ELISA, WB, IHC, IP, IF

Field of Research

Metabolism

Purification

Immunogen affinity purified

Dilution

WB: 1:500-1:1000; IP: 1:200-1:1000; IHC: 1:20-1:200; IF: 1:50-1:500

Purity

≥95% as determined by SDS-PAGE

Form

Liquid

Molecular Weight

28 kDa

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

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