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GALC antibody

Product Specifications

Background

This gene encodes a lysosomal protein which hydrolyzes the galactose ester bonds of galactosylceramide, galactosylsphingosine, lactosylceramide, and monogalactosyldiglyceride. Mutations in this gene have been associated with Krabbe disease, also known as globoid cell leukodystrophy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Synonyms

Galactocerebrosidase (GALCERase) |Galactocerebroside beta-galactosidase|Galactosylceramidase|Galactosylceramide beta-galactosidase|GALC

Gene ID

2581

UniProt

P54803

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Galactosylceramidase

Target

GALC

Clonality

Polyclonal

Isotype

IgG

Applications

ELISA, WB, IHC

Field of Research

Metabolism

Purification

Immunogen affinity purified

Dilution

WB: 1:500 - 1:2000; IHC: 1:50 - 1:100

Purity

≥95% as determined by SDS-PAGE

Form

Liquid

Molecular Weight

77 kDa

Shipping Conditions

4°C with ice bag

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Tested Applications

ELISA, WB, IHC

Immunogen Sequence

40-300aa

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