GADD45GIP1 antibody
Product Specifications
Background
Acts as a negative regulator of G1 to S cell cycle phase progression by inhibiting cyclin-dependent kinases. Inhibitory effects are additive with GADD45 proteins but occurs also in the absence of GADD45 proteins. Acts as a repressor of the orphan nuclear receptor NR4A1 by inhibiting AB domain-mediated transcriptional activity. May be involved in the hormone-mediated regulation of NR4A1 transcriptional activity. May play a role in mitochondrial protein synthesis.
Synonyms
Large ribosomal subunit protein mL64|39S ribosomal protein L59, mitochondrial (MRP-L59)|CKII beta-associating protein|CR6-interacting factor 1 (CRIF1)|Growth arrest and DNA damage-inducible proteins-interacting protein 1|Papillomavirus L2-interacting nuclear protein 1 (PLINP, PLINP-1)|p53-responsive gene 6 protein|GADD45GIP1|MRPL59|PLINP1|PRG6
Gene ID
90480
UniProt
Q8TAE8
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
growth arrest and DNA-damage-inducible, gamma interacting protein 1
Target
GADD45GIP1
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IP
Field of Research
Epigenetics
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IP: 1:200-1:2000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
25-28 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)
CAS Number
9007-83-4
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