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GADD45GIP1 antibody

Product Specifications

Background

Acts as a negative regulator of G1 to S cell cycle phase progression by inhibiting cyclin-dependent kinases. Inhibitory effects are additive with GADD45 proteins but occurs also in the absence of GADD45 proteins. Acts as a repressor of the orphan nuclear receptor NR4A1 by inhibiting AB domain-mediated transcriptional activity. May be involved in the hormone-mediated regulation of NR4A1 transcriptional activity. May play a role in mitochondrial protein synthesis.

Synonyms

Large ribosomal subunit protein mL64|39S ribosomal protein L59, mitochondrial (MRP-L59) |CKII beta-associating protein|CR6-interacting factor 1 (CRIF1) |Growth arrest and DNA damage-inducible proteins-interacting protein 1|Papillomavirus L2-interacting nuclear protein 1 (PLINP, PLINP-1) |p53-responsive gene 6 protein|GADD45GIP1|MRPL59|PLINP1|PRG6

Gene ID

90480

UniProt

Q8TAE8

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Growth arrest and DNA-damage-inducible, gamma interacting protein 1

Target

GADD45GIP1

Clonality

Polyclonal

Isotype

IgG

Applications

ELISA, WB, IP

Field of Research

Epigenetics

Purification

Immunogen affinity purified

Dilution

WB: 1:500-1:2000; IP: 1:200-1:2000

Purity

≥95% as determined by SDS-PAGE

Form

Liquid

Molecular Weight

25-28 kDa

Shipping Conditions

4°C with ice bag

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Tested Applications

ELISA, WB, IP

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