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GAA antibody

Product Specifications

Background

GAA (Alpha-1,4-glucosidase) is a lysosomal enzyme involved in the degradation of glycogen within cellular vacuoles. After translation, GAA undergoes proteolytic processing to form two lengths of lysosomal a-glucosidase, and both N-terminal and C-terminal processing occur. The full sequence can be further processed into a mature form. The 105 kDa GAA can be cleaved into 70 kDa or 76 kDa form.

Synonyms

Lysosomal alpha-glucosidase|Acid maltase|Aglucosidase alfa|76 kDa lysosomal alpha-glucosidase|70 kDa lysosomal alpha-glucosidase|GAA

Gene ID

2548

UniProt

P10253

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Lysosomal alpha-glucosidase

Target

GAA

Clonality

Polyclonal

Isotype

IgG

Applications

ELISA, WB, IHC, IP

Field of Research

Metabolism

Purification

Immunogen affinity purified

Dilution

WB: 1:500-1:1000; IP: 1:500-1:1000; IHC: 1:20-1:200

Purity

≥95% as determined by SDS-PAGE

Form

Liquid

Molecular Weight

70-76 kDa

Shipping Conditions

4°C with ice bag

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Tested Applications

ELISA, WB, IHC, IP

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