Antituberculosis agent-10
Antituberculosis agent-10 (Compound 9) has excellent antibacterial activity against Mycobacterium tuberculosis (MIC = 0.3 μM) . Antituberculosis agent-10 inhibits protein synthesis by targeting the 50S ribosomal subunit of the bacterium, thus exerting its antibacterial effect. Antituberculosis agent-10 is orally active[1].
Product Specifications
CAS Number
2095636-19-2
UNSPSC
12352005
Target
Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/antituberculosis-agent-10.html
Solubility
10 mM in DMSO
Smiles
O=C1O[C@@H](CN)CN1C2=CC=C(C3=CC=C(S(=O)(C)=O)C=C3)C(F)=C2
Molecular Formula
C17H17FN2O4S
Molecular Weight
364.39
References & Citations
[1]Boshoff HIM, et al. Mtb-Selective 5-Aminomethyl Oxazolidinone Prodrugs: Robust Potency and Potential Liabilities. ACS Infect Dis. 2024 Apr 6.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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