FXN antibody

FXN, also named as FRDA, X25, m81-FXN, d-FXN, m78-FXN and i-FXN, belongs to the frataxin family. It promotes the biosynthesis of heme and assembly and repair of iron-sulfur clusters by delivering Fe2+ to proteins involved in these pathways. FXN may play a role in the protection against iron-catalyzed oxidative stress through its ability to catalyze the oxidation of Fe2+ to Fe3+; the oligomeric form but not the monomeric form has in vitro ferroxidase activity. FXN is cleaved to be 4 chains. The mature form of FXN is 14 or 18kDa.

Frataxin, mitochondrial|Friedreich ataxia protein (Fxn) |Frataxin intermediate form (i-FXN) |Frataxin (56-210) Alternative names: m56-FXN|Frataxin (78-210) Alternative names: d-FXN|m78-FXN|Frataxin mature form Alternative names: Frataxin (81-210) |m81-FXN|Extramitochondrial frataxin|FXN|FRDA|X25