FLNB antibody
Product Specifications
Background
This gene encodes a member of the filamin family. The encoded protein interacts with glycoprotein Ib alpha as part of the process to repair vascular injuries. The platelet glycoprotein Ib complex includes glycoprotein Ib alpha, and it binds the actin cytoskeleton. Mutations in this gene have been found in several conditions: atelosteogenesis type 1 and type 3; boomerang dysplasia; autosomal dominant Larsen syndrome; and spondylocarpotarsal synostosis syndrome. Multiple alternatively spliced transcript variants that encode different protein isoforms have been described for this gene.
Synonyms
Filamin-B (FLN-B) |ABP-278|ABP-280 homolog|Actin-binding-like protein|Beta-filamin|Filamin homolog 1 (Fh1) |Filamin-3|Thyroid autoantigen|Truncated actin-binding protein (Truncated ABP) |FLNB|FLN1L|FLN3|TABP|TAP
Gene ID
2317
UniProt
O75369
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Filamin B, beta (actin binding protein 278)
Target
FLNB
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC
Field of Research
Signal Transduction, Developmental biology
Purification
Immunogen affinity purified
Dilution
WB: 1:500 - 1:1000; IHC: 1:20 - 1:50
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
298 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC
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