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FLI1 antibody

Product Specifications

Background

This gene encodes a transcription factor containing an ETS DNA-binding domain. The gene can undergo a t (11;22) (q24; q12) translocation with the Ewing sarcoma gene on chromosome 22, which results in a fusion gene that is present in the majority of Ewing sarcoma cases. An acute lymphoblastic leukemia-associated t (4;11) (q21; q23) translocation involving this gene has also been identified. Alternative splicing results in multiple transcript variants.

Synonyms

Friend leukemia integration 1 transcription factor|Proto-oncogene Fli-1|Transcription factor ERGB|FLI1

Gene ID

2313

UniProt

Q01543

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Friend leukemia virus integration 1

Target

FLI1

Clonality

Polyclonal

Isotype

IgG

Applications

ELISA, WB, IHC, IP

Field of Research

Epigenetics, Signal Transduction, Metabolism, Cancer, Immunology, Developmental biology

Purification

Immunogen affinity purified

Dilution

WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IP: 1:50 - 1:200

Purity

≥95% as determined by SDS-PAGE

Form

Liquid

Molecular Weight

43 kDa

Shipping Conditions

4°C with ice bag

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Tested Applications

ELISA, WB, IHC, IP

Immunogen Sequence

100-452aa

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