Human PSME3 / PA28g Protein, His Tag
Proteasome activator complex subunit 3 (PSME3), a member of the PA28 family, is also known as 11S regulator complex subunit gamma (REG-gamma), activator of multicatalytic protease subunit 3 and proteasome activator 28 subunit gamma (PA28gamma) . PSME3 activates the trypsin-like catalytic subunit of the proteasome but inhibits the chymotrypsin-like and postglutamyl-preferring (PGPH) subunits. PSME3 can also facilitate the MDM2-p53/TP53 interaction which promotes ubiquitination- and MDM2-dependent proteasomal degradation of p53/TP53, limiting its accumulation and resulting in inhibited apoptosis after DNA damage. Furthermore, PSME3 may also be involved in cell cycle regulation.
Product Specifications
Background
Specifications
Accession Number
P61289-1
Expression Region
Ala 2 - Tyr 254
Host
E. coli
Target
PSME3
Conjugation
Unconjugated
Tag
N-6xHis
Source
Human
Stability
Endotoxin
1.0 EU per μg
Purity
95%
Format
Powder
Buffer
50 mM Tris, 150 mM NaCl, pH7.5
Additives
Trehalose
Molecular Weight
30.3 kDa
Additionnal Information
Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/support/shipping-and-payments
Shipping Conditions
RT
Storage Conditions
-20°C
Package Size
100ug*1
Host or Source
E. coli
Species
Human
Protein ID
P61289-1
Preservative
Trehalose
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