FKBP8 antibody
Product Specifications
Background
Constitutively inactive PPiase, which becomes active when bound to calmodulin and calcium. Seems to act as a chaperone for BCL2, targets it to the mitochondria and modulates its phosphorylation state. The BCL2/FKBP8/calmodulin/calcium complex probably interferes with the binding of BCL2 to its targets. The active form of FKBP8 may therefore play a role in the regulation of apoptosis.
Synonyms
Peptidyl-prolyl cis-trans isomerase FKBP8 (PPIase FKBP8) |38 kDa FK506-binding protein (38 kDa FKBP, FKBP-38, hFKBP38) |FK506-binding protein 8 (FKBP-8) |FKBPR38|Rotamase|FKBP8|FKBP38
Gene ID
23770
UniProt
Q14318
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
FK506 binding protein 8, 38kDa
Target
FKBP8
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB
Field of Research
Signal Transduction, Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
53 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB
Frequently Asked Questions
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