FN1 antibody
Product Specifications
Background
Fibronectin 1 (FN1) is a high molecular weight glycoprotein which exists in both a soluble form in plasma (plasma FN1) and other body fluids and an insoluble form in the extracellular matrix (cellular FN1) . Plasma FN1 (dimeric form) is secreted by hepatocytes. Cellular FN (dimeric or cross-linked multimeric forms), made by fibroblasts, epithelial and other cell types, is deposited as fibrils in the extracellular matrix. FN1 binds to cell surfaces through integrins and to various compounds including collagen, fibrin and heparin. It is involved in cell adhesion and migration processes including embryogenesis, wound healing, hemostasis, host defense, and metastasis. (PMID: 7276612; 12244123; 12847088)
Synonyms
Fibronectin (FN) |Cold-insoluble globulin (CIG) |Anastellin|Ugl-Y1|Ugl-Y2|Ugl-Y3|FN1|FN
Gene ID
2335
UniProt
P02751
Host
Mouse
Reactivity
Human, Mouse
Immunogen
Fibronectin 1
Target
FN1
Clonality
Monoclonal
Isotype
IgG2a
Applications
ELISA, WB, IHC, IF
Field of Research
Stem Cells, Cancer, Signal Transduction
Purification
Protein A+G purification
Dilution
WB: 1:2000-1:10000; IHC: 1:300-1:1000; IF: 1:50-1:500
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
260 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Clone ID
3G6
Tested Applications
ELISA, WB, IHC, IF
Immunogen Sequence
2268-2477aa
Curated Selection
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