FERMT1 antibody
Product Specifications
Background
Involved in cell adhesion. Contributes to integrin activation. When coexpressed with talin, potentiates activation of ITGA2B. Required for normal keratinocyte proliferation. Required for normal polarization of basal keratinocytes in skin, and for normal cell shape. Required for normal adhesion of keratinocytes to fibronectin and laminin, and for normal keratinocyte migration to wound sites. May mediate TGF-beta 1 signaling in tumor progression.
Synonyms
Fermitin family homolog 1|Kindlerin|Kindlin syndrome protein|Kindlin-1|Unc-112-related protein 1|FERMT1|C20orf42|KIND1|URP1
Gene ID
55612
UniProt
Q9BQL6
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
fermitin family homolog 1(Drosophila)
Target
FERMT1
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC, IF
Field of Research
Signal Transduction, Immunology
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
70-77 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)
CAS Number
9007-83-4
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