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FERMT1 antibody

Product Specifications

Background

Involved in cell adhesion. Contributes to integrin activation. When coexpressed with talin, potentiates activation of ITGA2B. Required for normal keratinocyte proliferation. Required for normal polarization of basal keratinocytes in skin, and for normal cell shape. Required for normal adhesion of keratinocytes to fibronectin and laminin, and for normal keratinocyte migration to wound sites. May mediate TGF-beta 1 signaling in tumor progression.

Synonyms

Fermitin family homolog 1|Kindlerin|Kindlin syndrome protein|Kindlin-1|Unc-112-related protein 1|FERMT1|C20orf42|KIND1|URP1

Gene ID

55612

UniProt

Q9BQL6

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

Fermitin family homolog 1 (Drosophila)

Target

FERMT1

Clonality

Polyclonal

Isotype

IgG

Applications

ELISA, WB, IHC, IF

Field of Research

Signal Transduction, Immunology

Purification

Immunogen affinity purified

Dilution

WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200

Purity

≥95% as determined by SDS-PAGE

Form

Liquid

Molecular Weight

70-77 kDa

Shipping Conditions

4°C with ice bag

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Tested Applications

ELISA, WB, IHC, IF

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