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FAM3C antibody

Product Specifications

Background

FAM3C, also known as ILEI, is a secreted protein belonging to the cytokine-like protein family. FAM3C is a signaling cytokine with a GG domain, hydrophobic leader sequence and an N-terminal signal peptide. A change in expression of this protein has been noted in pancreatic cancer-derived cells. FAM3C has been involved in the epithelial to mesenchymal transition, and retinal laminar formation processes in vertebrates. Also, FAM3C may play an important role in inner ear development and thus be involved in cell differentiation and proliferation during inner ear embryogenesis.

Synonyms

Protein FAM3C|Interleukin-like EMT inducer|FAM3C|ILEI

Gene ID

10447

UniProt

Q92520

Host

Mouse

Reactivity

Human

Immunogen

family with sequence similarity 3, member C

Target

FAM3C

Clonality

Monoclonal

Isotype

IgG2a

Clone

2A10

Applications

ELISA, WB, IHC, IF

Field of Research

Cell Division and Proliferation, Signal Transduction

Purification

Protein A+G purification

Dilution

WB: 1:500-1:2000; IHC: 1:50-1:500; IF: 1:50-1:500

Purity

≥95% as determined by SDS-PAGE

Form

Liquid

Molecular Weight

25 kDa

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

CAS Number

9007-83-4

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