FAM3C antibody
Product Specifications
Background
FAM3C, also known as ILEI, is a secreted protein belonging to the cytokine-like protein family. FAM3C is a signaling cytokine with a GG domain, hydrophobic leader sequence and an N-terminal signal peptide. A change in expression of this protein has been noted in pancreatic cancer-derived cells. FAM3C has been involved in the epithelial to mesenchymal transition, and retinal laminar formation processes in vertebrates. Also, FAM3C may play an important role in inner ear development and thus be involved in cell differentiation and proliferation during inner ear embryogenesis.
Synonyms
Protein FAM3C|Interleukin-like EMT inducer|FAM3C|ILEI
Gene ID
10447
UniProt
Q92520
Host
Mouse
Reactivity
Human
Immunogen
Family with sequence similarity 3, member C
Target
FAM3C
Clonality
Monoclonal
Isotype
IgG2a
Applications
ELISA, WB, IHC, IF
Field of Research
Cell Division and Proliferation, Signal Transduction
Purification
Protein A+G purification
Dilution
WB: 1:500-1:2000; IHC: 1:50-1:500; IF: 1:50-1:500
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
25 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Clone ID
2A10
Tested Applications
ELISA, WB, IHC, IF
Immunogen Sequence
25-227aa
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