FABP3 antibody
Product Specifications
Background
The intracellular fatty acid-binding proteins (FABPs) belongs to a multigene family. FABPs are divided into at least three distinct types, namely the hepatic-, intestinal- and cardiac-type. They form 14-15 kDa proteins and are thought to participate in the uptake, intracellular metabolism and/or transport of long-chain fatty acids. They may also be responsible in the modulation of cell growth and proliferation. Fatty acid-binding protein 3 gene contains four exons and its function is to arrest growth of mammary epithelial cells. This gene is a candidate tumor suppressor gene for human breast cancer. Alternative splicing results in multiple transcript variants.
Synonyms
Fatty acid-binding protein, heart|Fatty acid-binding protein 3|Heart-type fatty acid-binding protein (H-FABP) |Mammary-derived growth inhibitor (MDGI) |Muscle fatty acid-binding protein (M-FABP) |FABP3|FABP11|MDGI
Gene ID
2170
UniProt
P05413
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Fatty acid binding protein 3, muscle and heart (mammary-derived growth inhibitor)
Target
FABP3
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC
Field of Research
Signal Transduction, Metabolism, Cardiovascular, Cancer, Developmental biology, Stem Cells
Purification
Immunogen affinity purified
Dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
14 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC
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