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FABP3 antibody

Product Specifications

Background

The intracellular fatty acid-binding proteins (FABPs) belongs to a multigene family. FABPs are divided into at least three distinct types, namely the hepatic-, intestinal- and cardiac-type. They form 14-15 kDa proteins and are thought to participate in the uptake, intracellular metabolism and/or transport of long-chain fatty acids. They may also be responsible in the modulation of cell growth and proliferation. Fatty acid-binding protein 3 gene contains four exons and its function is to arrest growth of mammary epithelial cells. This gene is a candidate tumor suppressor gene for human breast cancer. Alternative splicing results in multiple transcript variants.

Synonyms

Fatty acid-binding protein, heart|Fatty acid-binding protein 3|Heart-type fatty acid-binding protein (H-FABP) |Mammary-derived growth inhibitor (MDGI) |Muscle fatty acid-binding protein (M-FABP) |FABP3|FABP11|MDGI

Gene ID

2170

UniProt

P05413

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

Fatty acid binding protein 3, muscle and heart (mammary-derived growth inhibitor)

Target

FABP3

Clonality

Polyclonal

Isotype

IgG

Applications

ELISA, WB, IHC

Field of Research

Signal Transduction, Metabolism, Cardiovascular, Cancer, Developmental biology, Stem Cells

Purification

Immunogen affinity purified

Dilution

WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200

Purity

≥95% as determined by SDS-PAGE

Form

Liquid

Molecular Weight

14 kDa

Shipping Conditions

4°C with ice bag

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Tested Applications

ELISA, WB, IHC

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