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ETF1 antibody

Product Specifications

Background

Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA. Component of the transient SURF complex which recruits UPF1 to stalled ribosomes in the context of nonsense-mediated decay (NMD) of mRNAs containing premature stop codons.

Synonyms

Eukaryotic peptide chain release factor subunit 1 (Eukaryotic release factor 1, eRF1) |Protein Cl1|TB3-1|ETF1|ERF1|RF1|SUP45L1

Gene ID

2107

UniProt

P62495

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

Eukaryotic translation termination factor 1

Target

ETF1

Clonality

Polyclonal

Isotype

IgG

Applications

ELISA, WB, IHC, IF

Field of Research

Metabolism

Purification

Immunogen affinity purified

Dilution

WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200

Purity

≥95% as determined by SDS-PAGE

Form

Liquid

Molecular Weight

45-48 kDa

Shipping Conditions

4°C with ice bag

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Tested Applications

ELISA, WB, IHC, IF

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