ESX1 antibody
Product Specifications
Background
May coordinately regulate cell cycle progression and transcription during spermatogenesis. Inhibits degradation of polyubiquitinated cyclin A and cyclin B1 and thereby arrests the cell cycle at early M phase. ESXR1-N acts as a transcriptional repressor. Binds to the sequence 5'-TAATGTTATTA-3' which is present within the first intron of the KRAS gene and inhibits its expression. ESXR1-C has the ability to inhibit cyclin turnover.
Synonyms
Homeobox protein ESX1|Extraembryonic, spermatogenesis, homeobox 1|Homeobox protein ESX1-N|Homeobox protein ESX1-C|ESX1|ESX1L|ESX1R
Gene ID
80712
UniProt
Q8N693
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
ESX homeobox 1
Target
ESX1
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IP
Field of Research
Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IP: 1:200-1:2000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
65 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)
CAS Number
9007-83-4
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