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ESX1 antibody

Product Specifications

Background

May coordinately regulate cell cycle progression and transcription during spermatogenesis. Inhibits degradation of polyubiquitinated cyclin A and cyclin B1 and thereby arrests the cell cycle at early M phase. ESXR1-N acts as a transcriptional repressor. Binds to the sequence 5'-TAATGTTATTA-3' which is present within the first intron of the KRAS gene and inhibits its expression. ESXR1-C has the ability to inhibit cyclin turnover.

Synonyms

Homeobox protein ESX1|Extraembryonic, spermatogenesis, homeobox 1|Homeobox protein ESX1-N|Homeobox protein ESX1-C|ESX1|ESX1L|ESX1R

Gene ID

80712

UniProt

Q8N693

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

ESX homeobox 1

Target

ESX1

Clonality

Polyclonal

Isotype

IgG

Applications

ELISA, WB, IP

Field of Research

Metabolism

Purification

Immunogen affinity purified

Dilution

WB: 1:500-1:2000; IP: 1:200-1:2000

Purity

≥95% as determined by SDS-PAGE

Form

Liquid

Molecular Weight

65 kDa

Shipping Conditions

4°C with ice bag

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Tested Applications

ELISA, WB, IP

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