ERK1/2 antibody
Product Specifications
Background
ERK1 and ERK2 belongs to the protein kinase superfamily. It is involved in both the initiation and regulation of meiosis, mitosis, and postmitotic functions in differentiated cells by phosphorylating a number of transcription factors such as ELK-1. ERK1/2 catalized the reaction: ATP + a protein = ADP + a phosphoprotein. It is activated by tyrosine phosphorylation in response to insulin and NGF.
Synonyms
Mitogen-activated protein kinase 3 (MAP kinase 3, MAPK 3) |ERT2|Extracellular signal-regulated kinase 1 (ERK-1) |Insulin-stimulated MAP2 kinase|MAP kinase isoform p44 (p44-MAPK) |Microtubule-associated protein 2 kinase|p44-ERK1|MAPK3|ERK1|PRKM3
Gene ID
5595
UniProt
P27361
Host
Mouse
Reactivity
Human, Mouse
Immunogen
Mitogen-activated protein kinase 3
Target
ERK1/2
Clonality
Monoclonal
Isotype
IgG1
Applications
ELISA, WB, IHC, IF
Field of Research
Signal Transduction, Metabolism, Cardiovascular, Immunology, Neuroscience, Cell Division and Proliferation
Purification
Protein A+G purification
Dilution
WB:1:500-1:5000; IHC: 1:100-1:400; IF: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
38-44 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Clone ID
8C11
Tested Applications
ELISA, WB, IHC, IF
Immunogen Sequence
Peptide
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