ENSA antibody
Product Specifications
Background
Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A(PP2A) during mitosis. When phosphorylated at Ser-67 during mitosis, specifically interacts with PPP2R2D(PR55-delta) and inhibits its activity, leading to inactivation of PP2A, an essential condition to keep cyclin-B1-CDK1 activity high during M phase(By similarity). Also acts as a stimulator of insulin secretion by interacting with sulfonylurea receptor(ABCC8), thereby preventing sulfonylurea from binding to its receptor and reducing K(ATP) channel currents.
Synonyms
Alpha-endosulfine|ARPP-19e|ENSA
Gene ID
2029
UniProt
O43768
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
endosulfine alpha
Target
ENSA
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC
Field of Research
Neuroscience
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IHC: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
19 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)
CAS Number
9007-83-4
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
16761124 3 x 1.0μg DNA
CPNE3 CRISPRa sgRNA lentivector (set of three targets)(Mouse)
Ask
View Details 
20573124 3 x 1.0μg DNA
FKBP11 CRISPRa sgRNA lentivector (set of three targets)(Mouse)
Ask
View Details