ENPP6 antibody
Product Specifications
Background
Choline-specific glycerophosphodiester phosphodiesterase. The preferred substrate may be lysosphingomyelin(By similarity). Hydrolyzes lysophosphatidylcholine(LPC) to form monoacylglycerol and phosphorylcholine but not lysophosphatidic acid, showing it has a lysophospholipase C activity. Has a preference for LPC with short(12:0 and 14:0) or polyunsaturated(18:2 and 20:4) fatty acids. Also hydrolyzes glycerophosphorylcholine and sphingosylphosphorylcholine efficiently. Hydrolyzes the classical substrate for phospholipase C, p-nitrophenyl phosphorylcholine in vitro, while it does not hydrolyze the classical nucleotide phosphodiesterase substrate, p-nitrophenyl thymidine 5'-monophosphate. Does not hydrolyze diacyl phospholipids such as phosphatidylethanolamine, phosphatidylinositol, phosphatidylserine, phosphatidylglycerol and phosphatidic acid.
Synonyms
Glycerophosphocholine cholinephosphodiesterase ENPP6 (GPC-Cpde)|Choline-specific glycerophosphodiester phosphodiesterase|Ectonucleotide pyrophosphatase/phosphodiesterase family member 6 (E-NPP 6, NPP-6)|ENPP6
Gene ID
133121
UniProt
Q6UWR7
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
ectonucleotide pyrophosphatase/phosphodiesterase 6
Target
ENPP6
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB
Field of Research
Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
50 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)
CAS Number
9007-83-4
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