EDN1 antibody
Product Specifications
Background
This gene encodes a preproprotein that is proteolytically processed to generate a secreted peptide that belongs to the endothelin/sarafotoxin family. This peptide is a potent vasoconstrictor and its cognate receptors are therapeutic targets in the treatment of pulmonary arterial hypertension. Aberrant expression of this gene may promote tumorigenesis. Alternative splicing results in multiple transcript variants.
Synonyms
Endothelin-1|Preproendothelin-1 (PPET1) |Endothelin-1 (ET-1) |Big endothelin-1|EDN1
Gene ID
1906
UniProt
P05305
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Endothelin 1
Target
EDN1
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC
Field of Research
Immunology, Cardiovascular, Signal Transduction
Purification
Immunogen affinity purified
Dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:100
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
24 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC
More Discoveries
Explore Other Products
Browse additional items from our catalog
SHA4442 1 Each
2.8L Erlenmeyer flask platform with 3 clamps for NBS incubator shakers - EACH
Sign In for Pricing
View Details 
