EME1 antibody
Product Specifications
Background
Interacts with MUS81 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick. Typical substrates include 3'-flap structures, replication forks and nicked Holliday junctions. May be required in mitosis for the processing of stalled or collapsed replication forks.
Synonyms
Crossover junction endonuclease EME1|MMS4 homolog (hMMS4) |EME1|MMS4
Gene ID
146956
UniProt
Q96AY2
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Essential meiotic endonuclease 1 homolog 1 (S. pombe)
Target
EME1
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB
Field of Research
Stem Cells, Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
65 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB
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