EIF3M antibody
Product Specifications
Background
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC) . The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. May favor virus entry in case of infection with herpes simplex virus 1 (HSV1) or herpes simplex virus 2 (HSV2) .
Synonyms
Eukaryotic translation initiation factor 3 subunit M (eIF3m) |Fetal lung protein B5 (hFL-B5) |PCI domain-containing protein 1|EIF3M|HFLB5|PCID1
Gene ID
10480
UniProt
Q7L2H7
Host
Mouse
Reactivity
Human
Immunogen
Eukaryotic translation initiation factor 3, subunit M
Target
EIF3M
Clonality
Monoclonal
Isotype
IgG1
Applications
ELISA, WB, IF
Field of Research
Metabolism
Purification
Protein A+G purification
Dilution
WB: 1:500-1:2000; IF: 1:10-1:100
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
43 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Clone ID
1A4
Tested Applications
ELISA, WB, IF
Immunogen Sequence
1-374aa
Curated Selection
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