EIF3K antibody
Product Specifications
Background
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC) . The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation.
Synonyms
Eukaryotic translation initiation factor 3 subunit K (eIF3k) |Eukaryotic translation initiation factor 3 subunit 12|Muscle-specific gene M9 protein|PLAC-24|eIF-3 p25|eIF-3 p28|EIF3K|EIF3S12
Gene ID
27335
UniProt
Q9UBQ5
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Eukaryotic translation initiation factor 3, subunit K
Target
EIF3K
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA
Field of Research
Metabolism
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA
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