EIF3I antibody

Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC) . The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation.

Eukaryotic translation initiation factor 3 subunit I (eIF3i) |Eukaryotic translation initiation factor 3 subunit 2|TGF-beta receptor-interacting protein 1 (TRIP-1) |eIF-3-beta|eIF3 p36|EIF3I|EIF3S2|TRIP1