EIF3I antibody
Product Specifications
Background
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC) . The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation.
Synonyms
Eukaryotic translation initiation factor 3 subunit I (eIF3i) |Eukaryotic translation initiation factor 3 subunit 2|TGF-beta receptor-interacting protein 1 (TRIP-1) |eIF-3-beta|eIF3 p36|EIF3I|EIF3S2|TRIP1
Gene ID
8668
UniProt
Q13347
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Eukaryotic translation initiation factor 3, subunit I
Target
EIF3I
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, IHC, IF, IP, WB, FC
Field of Research
Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200; IF: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
36 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, IHC, IF, IP, WB, FC
Curated Selection
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