EIF3G antibody

Component of the eukaryotic translation initiation factor 3(eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex(43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. This subunit can bind 18S rRNA. In case of FCV infection, plays a role in the ribosomal termination-reinitiation event leading to the translation of VP2(PubMed:18056426).

Eukaryotic translation initiation factor 3 subunit G (eIF3g)|Eukaryotic translation initiation factor 3 RNA-binding subunit (eIF-3 RNA-binding subunit)|Eukaryotic translation initiation factor 3 subunit 4|eIF-3-delta|eIF3 p42|eIF3 p44|EIF3G|EIF3S4