SLC1A2 antibody
Product Specifications
Background
EAAT2 (also known as GLT-1), is encoded by SLC1A2 and is a glutamate transporter which can clear the majority of extracellular glutamate in brain and prevent brain seizures.Three isoforms of EAAT2 exist due to the alternative splicing. In addition to the 65-70 kDa monomer form, 120-140 kDa dimer of EAAT2 can also be observed on SDS-PAGE. (PMID: 22114258)
Synonyms
Excitatory amino acid transporter 2|Glutamate/aspartate transporter II|Sodium-dependent glutamate/aspartate transporter 2|Solute carrier family 1 member 2|SLC1A2|EAAT2|GLT1
Gene ID
6506
UniProt
P43004
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Solute carrier family 1 (glial high affinity glutamate transporter), member 2
Target
SLC1A2
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC
Field of Research
Signal Transduction, Metabolism, Developmental biology, Neuroscience, Stem Cells
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IHC: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
60-70 kDa, 120 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC
Immunogen Sequence
494-574aa
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