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SLC1A2 antibody

Product Specifications

Background

EAAT2 (also known as GLT-1), is encoded by SLC1A2 and is a glutamate transporter which can clear the majority of extracellular glutamate in brain and prevent brain seizures.Three isoforms of EAAT2 exist due to the alternative splicing. In addition to the 65-70 kDa monomer form, 120-140 kDa dimer of EAAT2 can also be observed on SDS-PAGE. (PMID: 22114258)

Synonyms

Excitatory amino acid transporter 2|Glutamate/aspartate transporter II|Sodium-dependent glutamate/aspartate transporter 2|Solute carrier family 1 member 2|SLC1A2|EAAT2|GLT1

Gene ID

6506

UniProt

P43004

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Solute carrier family 1 (glial high affinity glutamate transporter), member 2

Target

SLC1A2

Clonality

Polyclonal

Isotype

IgG

Applications

ELISA, WB, IHC

Field of Research

Signal Transduction, Metabolism, Developmental biology, Neuroscience, Stem Cells

Purification

Immunogen affinity purified

Dilution

WB: 1:500-1:2000; IHC: 1:20-1:200

Purity

≥95% as determined by SDS-PAGE

Form

Liquid

Molecular Weight

60-70 kDa, 120 kDa

Shipping Conditions

4°C with ice bag

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Tested Applications

ELISA, WB, IHC

Immunogen Sequence

494-574aa

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