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DTX4 antibody

Product Specifications

Background

Regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations (By similarity) . Functions as a ubiquitin ligase protein in vivo, mediating 'Lys48'-linked polyubiquitination and promoting degradation of TBK1, targeting to TBK1 requires interaction with NLRP4.

Synonyms

E3 ubiquitin-protein ligase DTX4|Protein deltex-4 (Deltex4) |RING finger protein 155|RING-type E3 ubiquitin transferase DTX4|DTX4|KIAA0937|RNF155

Gene ID

23220

UniProt

Q9Y2E6

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

Deltex homolog 4 (Drosophila)

Target

DTX4

Clonality

Polyclonal

Isotype

IgG

Applications

ELISA, WB, IF

Field of Research

Signal Transduction, Metabolism, Developmental biology

Purification

Immunogen affinity purified

Dilution

WB: 1:500-1:2000; IF: 1:20-1:200

Purity

≥95% as determined by SDS-PAGE

Form

Liquid

Molecular Weight

67-70 kDa

Shipping Conditions

4°C with ice bag

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Tested Applications

ELISA, WB, IF

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