DTX4 antibody
Product Specifications
Background
Regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations(By similarity). Functions as a ubiquitin ligase protein in vivo, mediating 'Lys48'-linked polyubiquitination and promoting degradation of TBK1, targeting to TBK1 requires interaction with NLRP4.
Synonyms
E3 ubiquitin-protein ligase DTX4|Protein deltex-4 (Deltex4)|RING finger protein 155|RING-type E3 ubiquitin transferase DTX4|DTX4|KIAA0937|RNF155
Gene ID
23220
UniProt
Q9Y2E6
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
deltex homolog 4(Drosophila)
Target
DTX4
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IF
Field of Research
Signal Transduction, Metabolism, Developmental biology
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IF: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
67-70 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)
CAS Number
9007-83-4
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