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DDC antibody

Product Specifications

Background

Aromatic-L-amino-acid decarboxylase belongs to the pyridoxal-dependent aminotransferase superfamily.DDC catalyzes the decarboxylation of L-3,4-dihydroxyphenylalanine(DOPA) to dopamine, L-5-hydroxytryptophan to serotonin and L-tryptophan to tryptamine.DDC is the cause of aromatic L-amino-acid decarboxylase deficiency(AADCD).Researches showed that Ddc is only one of the enzymes in the biosynthetic pathways for bioamines and catecholamines.

Synonyms

Aromatic-L-amino-acid decarboxylase (AADC)|DOPA decarboxylase (DDC)|DDC|AADC

UniProt

P20711

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

dopa decarboxylase

Target

DDC

Clonality

Polyclonal

Isotype

IgG

Applications

ELISA, WB, IHC, IP

Field of Research

Neuroscience, Cancer, Metabolism

Purification

Immunogen affinity purified

Dilution

WB: 1:500-1:1000; IP: 1:500-1:1000; IHC: 1:20-1:200

Purity

≥95% as determined by SDS-PAGE

Form

Liquid

Molecular Weight

54 kDa

Storage Conditions

PBS with 0.1% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

CAS Number

9007-83-4

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