DOC2B antibody

Product Specifications

Background

Calcium sensor which positively regulates SNARE-dependent fusion of vesicles with membranes. Binds phospholipids in a calcium-dependent manner and may act at the priming stage of fusion by modifying membrane curvature to stimulate fusion. Involved in calcium-triggered exocytosis in chromaffin cells and calcium-dependent spontaneous release of neurotransmitter in absence of action potentials in neuronal cells. Involved both in glucose-stimulated insulin secretion in pancreatic cells and insulin-dependent GLUT4 transport to the plasma membrane in adipocytes (By similarity) .

Synonyms

Double C2-like domain-containing protein beta (Doc2-beta) |DOC2B|DOC2BL

Gene ID

8447

UniProt

Q14184

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Double C2-like domains, beta

Target

DOC2B

Clonality

Polyclonal

Isotype

IgG

Applications

ELISA, WB, IF

Field of Research

Neuroscience

Purification

Immunogen affinity purified

Dilution

WB: 1:500-1:2000; IF: 1:20-1:200

Purity

≥95% as determined by SDS-PAGE

Form

Liquid

Molecular Weight

46 kDa

Shipping Conditions

4°C with ice bag

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Tested Applications

ELISA, WB, IF

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

PA15442-01 50 μL

Rabbit Anti-Human CSRNP1 pAb

Ask

View Details

PA15442-02 100 μL

Rabbit Anti-Human CSRNP1 pAb

Ask

View Details

EKN50628 96 Tests

Human Pleiotrophin (PTN) CLIA Kit

Ask

View Details

MBS1162400-01 1 mg (E-Coli)

Recombinant Danio rerio Nck-associated protein 1 (nckap1), partial

Ask

View Details

MBS1162400-02 1 mg (Yeast)

Recombinant Danio rerio Nck-associated protein 1 (nckap1), partial

Ask

View Details

ABP-S-02311 5 Plates

Mouse TGF beta Receptor 2 Matched Antibody Pair Set [ABP-S-02311]

Ask

View Details