DNMT3A antibody
Product Specifications
Background
CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase that is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes to the cytoplasm and nucleus and its expression is developmentally regulated.
Synonyms
DNA (cytosine-5) -methyltransferase 3A (Dnmt3a) |Cysteine methyltransferase DNMT3A|DNA methyltransferase HsaIIIA (DNA MTase HsaIIIA, M.HsaIIIA) |DNMT3A
Gene ID
1788
UniProt
Q9Y6K1
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
DNA (cytosine-5-) -methyltransferase 3 alpha
Target
DNMT3A
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC, IF
Field of Research
Epigenetics, Metabolism, Developmental biology
Purification
Immunogen affinity purified
Dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
95 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC, IF
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