DLX5 antibody
Product Specifications
Background
Transcriptional factor involved in bone development. Acts as an immediate early BMP-responsive transcriptional activator essential for osteoblast differentiation. Stimulates ALPL promoter activity in a RUNX2-independent manner during osteoblast differentiation. Stimulates SP7 promoter activity during osteoblast differentiation. Promotes cell proliferation by up-regulating MYC promoter activity. Involved as a positive regulator of both chondrogenesis and chondrocyte hypertrophy in the endochondral skeleton. Binds to the homeodomain-response element of the ALPL and SP7 promoter. Binds to the MYC promoter. Requires the 5'-TAATTA-3' consensus sequence for DNA-binding.
Synonyms
Homeobox protein DLX-5|DLX5
Gene ID
1749
UniProt
P56178
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
distal-less homeobox 5
Target
DLX5
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA
Field of Research
Neuroscience, Stem Cells, Metabolism, Developmental biology
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)
CAS Number
9007-83-4
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