DIS3L antibody
Product Specifications
Background
Putative cytoplasm-specific catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs containing AU-rich elements(AREs) within their 3' untranslated regions, and in RNA surveillance pathways, preventing translation of aberrant mRNAs. It seems to be involved in degradation of histone mRNA.
Synonyms
DIS3-like exonuclease 1|DIS3L|DIS3L1|KIAA1955
Gene ID
115752
UniProt
Q8TF46
Host
Rabbit
Reactivity
Human
Immunogen
DIS3 mitotic control homolog-like
Target
DIS3L
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB
Field of Research
Cell Division and Proliferation, Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
121 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)
CAS Number
9007-83-4
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