DHX9 antibody
Product Specifications
Background
Unwinds double-stranded DNA and RNA in a 3' to 5' direction. Alteration of secondary structure may subsequently influence interactions with proteins or other nucleic acids. Functions as a transcriptional activator. Component of the CRD-mediated complex that promotes MYC mRNA stability. Involved with LARP6 in the stabilization of type I collagen mRNAs for CO1A1 and CO1A2. As component of a large PER complex is involved in the inhibition of 3' transcriptional termination of circadian target genes such as PER1 and NR1D1 and the control of the circadian rhythms. Positively regulates HIV-1 LTR-directed gene expression.
Synonyms
ATP-dependent RNA helicase A|DEAH box protein 9|DExH-box helicase 9|Leukophysin (LKP) |Nuclear DNA helicase II (NDH II) |RNA helicase A|DHX9|DDX9|LKP|NDH2
Gene ID
1660
UniProt
Q08211
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
DEAH (Asp-Glu-Ala-His) box polypeptide 9
Target
DHX9
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC, IF
Field of Research
Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:1000-1:4000; IHC: 1:20-1:200; IF: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
140 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC, IF
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