DGKH antibody
Product Specifications
Background
Phosphorylates diacylglycerol(DAG) to generate phosphatidic acid(PA). Plays a key role in promoting cell growth. Activates the Ras/B-Raf/C-Raf/MEK/ERK signaling pathway induced by EGF. Regulates the recruitment of RAF1 and BRAF from cytoplasm to membranes and their heterodimerization.
Synonyms
Diacylglycerol kinase eta (DAG kinase eta)|Diglyceride kinase eta (DGK-eta)|DGKH
Gene ID
160851
UniProt
Q86XP1
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
diacylglycerol kinase, eta
Target
DGKH
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC, IP, IF
Field of Research
Signal Transduction, Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IP: 1:200-1:2000; IHC: 1:50-1:500; IF: 1:50-1:500
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
135 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)
CAS Number
9007-83-4
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