DGAT1 antibody
Product Specifications
Background
Catalyzes the terminal and only committed step in triacylglycerol synthesis by using diacylglycerol and fatty acyl CoA as substrates. In contrast to DGAT2 it is not essential for survival. May be involved in VLDL (very low density lipoprotein) assembly. In liver, plays a role in esterifying exogenous fatty acids to glycerol. Functions as the major acyl-CoA retinol acyltransferase (ARAT) in the skin, where it acts to maintain retinoid homeostasis and prevent retinoid toxicity leading to skin and hair disorders.
Synonyms
Diacylglycerol O-acyltransferase 1|ACAT-related gene product 1|Acyl-CoA retinol O-fatty-acyltransferase (ARAT, Retinol O-fatty-acyltransferase) |Diglyceride acyltransferase|DGAT1|AGRP1|DGAT
Gene ID
8694
UniProt
O75907
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Diacylglycerol O-acyltransferase homolog 1 (Mouse)
Target
DGAT1
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC, IP
Field of Research
Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
55 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC, IP
Immunogen Sequence
1-90
Curated Selection
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