DCX antibody
Product Specifications
Background
Microtubule-associated protein required for initial steps of neuronal dispersion and cortex lamination during cerebral cortex development. May act by competing with the putative neuronal protein kinase DCLK1 in binding to a target protein. May in that way participate in a signaling pathway that is crucial for neuronal interaction before and during migration, possibly as part of a calcium ion-dependent signal transduction pathway. May be part with PAFAH1B1/LIS-1 of overlapping, but distinct, signaling pathways that promote neuronal migration.
Synonyms
Neuronal migration protein doublecortin|Doublin|Lissencephalin-X (Lis-X)|DCX|DBCN|LISX
Gene ID
1641
UniProt
O43602
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
doublecortin
Target
DCX
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC, IF
Field of Research
Neuroscience, Stem Cells, Signal Transduction, Developmental biology
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IF: 1:20-1:200; IHC: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
40 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)
CAS Number
9007-83-4
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