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DCX antibody

Product Specifications

Background

Microtubule-associated protein required for initial steps of neuronal dispersion and cortex lamination during cerebral cortex development. May act by competing with the putative neuronal protein kinase DCLK1 in binding to a target protein. May in that way participate in a signaling pathway that is crucial for neuronal interaction before and during migration, possibly as part of a calcium ion-dependent signal transduction pathway. May be part with PAFAH1B1/LIS-1 of overlapping, but distinct, signaling pathways that promote neuronal migration.

Synonyms

Neuronal migration protein doublecortin|Doublin|Lissencephalin-X (Lis-X) |DCX|DBCN|LISX

Gene ID

1641

UniProt

O43602

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Doublecortin

Target

DCX

Clonality

Polyclonal

Isotype

IgG

Applications

ELISA, WB, IHC, IF

Field of Research

Neuroscience, Stem Cells, Signal Transduction, Developmental biology

Purification

Immunogen affinity purified

Dilution

WB: 1:500-1:2000; IF: 1:20-1:200; IHC: 1:20-1:200

Purity

≥95% as determined by SDS-PAGE

Form

Liquid

Molecular Weight

40 kDa

Shipping Conditions

4°C with ice bag

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Tested Applications

ELISA, WB, IHC, IF

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