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DBF4 antibody

Product Specifications

Background

Regulatory subunit for CDC7 which activates its kinase activity thereby playing a central role in DNA replication and cell proliferation. Required for progression of S phase. The complex CDC7-DBF4A selectively phosphorylates MCM2 subunit at 'Ser-40' and 'Ser-53' and then is involved in regulating the initiation of DNA replication during cell cycle.

Synonyms

Protein DBF4 homolog A|Activator of S phase kinase|Chiffon homolog A|DBF4-type zinc finger-containing protein 1|DBF4|ASK|DBF4A|ZDBF1

Gene ID

10926

UniProt

Q9UBU7

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

DBF4 homolog

Target

DBF4

Clonality

Polyclonal

Isotype

IgG

Applications

ELISA, WB

Field of Research

Metabolism

Purification

Immunogen affinity purified

Dilution

WB: 1:500-1:2000

Purity

≥95% as determined by SDS-PAGE

Form

Liquid

Molecular Weight

70-80 kDa

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

CAS Number

9007-83-4

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