DBF4 antibody
Product Specifications
Background
Regulatory subunit for CDC7 which activates its kinase activity thereby playing a central role in DNA replication and cell proliferation. Required for progression of S phase. The complex CDC7-DBF4A selectively phosphorylates MCM2 subunit at 'Ser-40' and 'Ser-53' and then is involved in regulating the initiation of DNA replication during cell cycle.
CAS Number
9007-83-4
Synonyms
Protein DBF4 homolog A|Activator of S phase kinase|Chiffon homolog A|DBF4-type zinc finger-containing protein 1|DBF4|ASK|DBF4A|ZDBF1
Gene ID
10926
UniProt
Q9UBU7
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
DBF4 homolog
Target
DBF4
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB
Field of Research
Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
70-80 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)
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