KRT19 antibody
Product Specifications
Background
The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells. KRT19, one of type I keratins, is specifically expressed in the periderm, the transiently superficial layer that envelopes the developing epidermis. Due to its high sensitivity, KRT19 is the most used marker for detection of tumor cells disseminated in lymph nodes, peripheral blood, and bone marrow of breast cancer patients. This antibody, generated against full length KRT19 protein, also recognizes KRT17, another type I keratin homologous to KRT19. KRT17 is used as a marker for trauma.
Synonyms
Keratin, type I cytoskeletal 19|Cytokeratin-19 (CK-19)|Keratin-19 (K19)|KRT19
Gene ID
3880
UniProt
P08727
Host
Mouse
Reactivity
Human
Immunogen
keratin 19
Target
KRT19
Clonality
Monoclonal
Isotype
IgG2a
Clone
2F9
Applications
ELISA, WB, IHC
Field of Research
Stem Cells, Immunology, Cancer
Purification
Protein A+G purification
Dilution
WB: 1:500-1:5000; IHC: 1:50-1:500
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
44-50 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)
CAS Number
9007-83-4
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