CDO1 antibody
Product Specifications
Background
CDO1(cysteine dioxygenase type 1) is also named as CDO and belongs to the cysteine dioxygenase family. It is an enzyme that adds molecular oxygen to the sulfur of cysteine, converting the thiol to a sulfinic acid known as cysteinesulfinic acid(3-sulfinoalanine) and CDO1 is one of the most highly regulated metabolic enzymes responding to diet(PMID:19011731). The expression of CDO can significantly decrease the level of intracellular cysteine and this reduction is also associated with a decrease in total glutathione levels(PMID:17327371). Cysteine dioxygenase(CDO) plays a critical role in the regulation of cellular cysteine concentration andmultiple forms of CDO(23 kDa, 25 kDa, and 68 kDa) have been claimed based upon separation and detection using S
Synonyms
Cysteine dioxygenase type 1|Cysteine dioxygenase type I (CDO, CDO-I)|CDO1
UniProt
Q16878
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
cysteine dioxygenase, type I
Target
CDO1
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC, IP
Field of Research
Signal Transduction, Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:200-1:2000; IP: 1:200-1:2000; IHC: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
23 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)
CAS Number
9007-83-4
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