CYP51A1 antibody
Product Specifications
Background
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein participates in the synthesis of cholesterol by catalyzing the removal of the 14alpha-methyl group from lanosterol. Homologous genes are found in all three eukaryotic phyla, fungi, plants, and animals, suggesting that this is one of the oldest cytochrome P450 genes. Two transcript variants encoding different isoforms have been found for this gene.
Synonyms
Lanosterol 14-alpha demethylase (LDM) |CYPLI|Cytochrome P450 51A1 (CYP51A1) |Cytochrome P450-14DM (Cytochrome P45014DM) |Cytochrome P450LI|Sterol 14-alpha demethylase|CYP51A1|CYP51
Gene ID
1595
UniProt
Q16850
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Cytochrome P450, family 51, subfamily A, polypeptide 1
Target
CYP51A1
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC
Field of Research
Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
63 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC
Curated Selection
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