CYP4F8 antibody
Product Specifications
Background
Hydroxylates arachidonic acid(20:4n-6) to(18R)-hydroxyarachidonate. Shows little activity against prostaglandin(PG) D2, PGE1, PGE2, PGF2alpha, and leukotriene B4. Catalyzes omega-2 and omega-3-hydroxylation of PGH1 and PGH2. Catalyzes epoxidation of 4,7,10,13,16,19-(Z)-docosahexaenoic acid(22:6n-3) and 7,10,13,16,19-(Z)-docosapentaenoic acid(22:5n-3) and omega-3-hydroxylation of 4,7,10,13,16-(Z)-docosapentaenoic acid(22:5n-6). Catalyzes hydroxylation of PGI2 and carbaprostacyclin.
Synonyms
Cytochrome P450 4F8|CYPIVF8|CYP4F8
Gene ID
11283
UniProt
P98187
Host
Rabbit
Reactivity
Human
Immunogen
cytochrome P450, family 4, subfamily F, polypeptide 8
Target
CYP4F8
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, IHC
Field of Research
Metabolism
Purification
Immunogen affinity purified
Dilution
IHC: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)
CAS Number
9007-83-4
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