CYP4F11 antibody
Product Specifications
Background
Omega-hydroxylase that oxidizes a variety of structurally unrelated compounds, including fatty acids and xenobiotics. Plays a key role in vitamin K catabolism by mediating omega-hydroxylation of vitamin K1(phylloquinone), and menaquinone-4(MK-4), a form of vitamin K2. Hydroxylation of phylloquinone and MK-4 probably regulates blood coagulation(PubMed:24138531). Catalyzes omega-hydroxylation of 3-hydroxy fatty acids, such as 3-hydroxypalmitate, 3-hydroxyoleate, 3-hydroxyarachidonate, and 3-hydroxystearate(PubMed:18065749, PubMed:19932081). Oxidizes drugs such as erythromycin, benzphetamine, ethylmorphine, chlorpromazine and imipramine(PubMed:15364545).
Synonyms
Cytochrome P450 4F11 (CYPIVF11)|3-hydroxy fatty acids omega-hydroxylase CYP4F11|Docosahexaenoic acid omega-hydroxylase|Long-chain fatty acid omega-monooxygenase|Phylloquinone omega-hydroxylase CYP4F11|CYP4F11
Gene ID
57834
UniProt
Q9HBI6
Host
Rabbit
Reactivity
Human
Immunogen
cytochrome P450, family 4, subfamily F, polypeptide 11
Target
CYP4F11
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC
Field of Research
Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IHC: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
57 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)
CAS Number
9007-83-4
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