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CYP2A6 antibody

Product Specifications

Background

Exhibits a high coumarin 7-hydroxylase activity. Can act in the hydroxylation of the anti-cancer drugs cyclophosphamide and ifosphamide. Competent in the metabolic activation of aflatoxin B1. Constitutes the major nicotine C-oxidase. Acts as a 1,4-cineole 2-exo-monooxygenase. Possesses low phenacetin O-deethylation activity.

Synonyms

Cytochrome P450 2A6|1,4-cineole 2-exo-monooxygenase|CYPIIA6|Coumarin 7-hydroxylase|Cytochrome P450 IIA3|Cytochrome P450(I)|CYP2A6|CYP2A3

Gene ID

1548

UniProt

P11509

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

cytochrome P450, family 2, subfamily A, polypeptide 6

Target

CYP2A6

Clonality

Polyclonal

Isotype

IgG

Applications

ELISA, IHC, WB

Field of Research

Metabolism

Purification

Immunogen affinity purified

Dilution

WB: 1:500-1:2000; IHC: 1:50-1:500

Purity

≥95% as determined by SDS-PAGE

Form

Liquid

Molecular Weight

50 kDa

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

CAS Number

9007-83-4

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