CYP2A6 antibody
Product Specifications
Background
Exhibits a high coumarin 7-hydroxylase activity. Can act in the hydroxylation of the anti-cancer drugs cyclophosphamide and ifosphamide. Competent in the metabolic activation of aflatoxin B1. Constitutes the major nicotine C-oxidase. Acts as a 1,4-cineole 2-exo-monooxygenase. Possesses low phenacetin O-deethylation activity.
Synonyms
Cytochrome P450 2A6|1,4-cineole 2-exo-monooxygenase|CYPIIA6|Coumarin 7-hydroxylase|Cytochrome P450 IIA3|Cytochrome P450 (I) |CYP2A6|CYP2A3
Gene ID
1548
UniProt
P11509
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Cytochrome P450, family 2, subfamily A, polypeptide 6
Target
CYP2A6
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, IHC, WB
Field of Research
Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IHC: 1:50-1:500
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
50 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, IHC, WB
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