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PPIA antibody

Product Specifications

Background

This gene encodes a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. The encoded protein is a cyclosporin binding-protein and may play a role in cyclosporin A-mediated immunosuppression. The protein can also interact with several HIV proteins, including p55 gag, Vpr, and capsid protein, and has been shown to be necessary for the formation of infectious HIV virions. Multiple pseudogenes that map to different chromosomes have been reported.

Synonyms

Peptidyl-prolyl cis-trans isomerase A (PPIase A) |Cyclophilin A|Cyclosporin A-binding protein|Rotamase A|Peptidyl-prolyl cis-trans isomerase A, N-terminally processed|PPIA|CYPA

Gene ID

5479

UniProt

P62937

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Peptidylprolyl isomerase A (cyclophilin A)

Target

PPIA

Clonality

Polyclonal

Isotype

IgG

Applications

ELISA, WB

Field of Research

Metabolism

Purification

Immunogen affinity purified

Dilution

WB: 1:500-1:2000

Purity

≥95% as determined by SDS-PAGE

Form

Liquid

Molecular Weight

18 kDa

Shipping Conditions

4°C with ice bag

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Tested Applications

ELISA, WB

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